KHAS CORE Talks – Dr. Nuray Söğünmez Erdoğan
KHAS CORE Talks series continues with Dr. Nuray Söğünmez Erdoğan‘s speech entitled “Solving the Biological Complexity with Data-Driven Machine Learning Methods”.
You can follow the speech on Tuesday, December 28 at 15:00 on Zoom.
Please fill the registration form in advance:
https://us02web.zoom.us/meeting/register/tZAtdO-hpjkjG9JbLNlg9igJwasi4S1AGKjU
Abstract: Biology and its tools have been used since ancient times to understand nature and find cures to diseases, and from then, its applications evolved with an extraordinary speed. Biological interactions in organisms are complex and require interdisciplinary complex systems understanding. This complexity begins with the number of protein-encoding genes found in human cells. Each cell in the body shares the same genes, but their combinatorial expression levels (transcripts and proteins) result in diverse cell- and tissue types. Therefore, biological complexity increases in the transcript and protein levels. Considering that the Human Genome Project took 13 years to complete the sequencing of human reference genome data, understanding the human transcriptome and proteome map is in its very early days.
This talk focuses on a recently developed state-of-the-art technology field called single-cell omics. Its application areas, together with its limitations, will be explained. These limitations can be elucidated with interdisciplinary approaches. Our newly developed machine learning method is successfully applied to solve one of the current problems in the single-cell omics field. This talk will cover how one significant feature of nature was used to decipher this current problem. Finally, the importance of this analysis for integrating high-dimensional biological data and the relevance of creating cellular maps in organisms will be clarified.
About the Speaker: Nuray Söğünmez Erdoğan received her B.Sc. and M.Sc. degrees from Boğaziçi University Department of Molecular Biology and Genetics. She received her Ph.D. degree from Kadir Has University Department of Bioinformatics and Genetics. She continued her postdoctoral studies in Kadir Has University NODDS Laboratory and focused on solving complex biological systems problems with interdisciplinary approaches. She is currently working as a Core Program Instructor at Kadir Has University. She has worked on different projects related to transgene applications in sensory systems, precision medicine and personalized treatments, and protein allostery and dynamics.